5 (1.9), 1.2 (0.96) and 14 (10.8), respectively. Values in both matrices remained high even when potential factors such as secondhand smoking, dental amalgam, and/or fish consumption excluded. RV95s for metals in blood were generally higher than in other countries, except for mercury in Riyadh samples, which was also 4-fold lower than in Al-Kharj. However, due to the time lag between the two studies, and since the Al-Kharj study was conducted 13 years ago, the most recent RV95s derived from the Riyadh study are recommended for Saudi women living in the Central region. The RV95s for urinary mercury and cadmium were comparable to other countries, but lead requires closer attention. To our knowledge, this study is the first to propose RV95s for mercury, cadmium, and lead in blood and urine of Saudi women of childbearing age, a population that is highly susceptible to the adverse health effects of these metals. Reactive chemistry is ubiquitous indoors with a wealth of complex oxidation reactions; some of these are initiated by both homogeneous and heterogeneous reaction of ozone with unsaturated organic compounds and subsequent the hydroxyl radical, either in the gas-phase or on reactive surfaces. One major focus has been the reaction of common and abundant terpene-based fragrances in indoor air emitted from many wood-based materials, a variety of consumer products, and citrus fruits and flowers. Inhalation of the terpenes themselves are generally not considered a health concern (both acute and long-term) due to their low indoor air concentrations; however, their gas- and surface reactions with ozone and the hydroxyl radical produce a host of products, both gaseous, i. a. formaldehyde, and ultrafine particles formed by condensation/nucleation processes. click here These reaction products may be of health concern. Human cell bioassays with key reaction products from ozone-initiated terpene reactions have shown some inflammatory reactions, but results are difficult to interpret for human exposure and risk assessment. Acute effects like sensory irritation in eyes and airways are unlikely or present at very low intensity in real life conditions based on rodent and human exposure studies and known thresholds for sensory irritation in eyes and airways and derived human reference values for airflow limitation and pulmonary irritation. Some fragrances and their ozone-initiated reaction products may possess anti-inflammatory properties. However, long-term effects of the reaction products as ultrafine particles are poorly explored. Material and product surfaces with high ozone deposition velocities may significantly impact the perceived air quality by altered emissions from both homogeneous and heterogeneous surface reactions. Published by Elsevier GmbH.The chemical synthesis of pyridoxine-5'-β-d-glucoside (5'-β-PNG) was investigated using various glucoside donors and promoters. Hereby, the combination of α4,3-O-isopropylidene pyridoxine, glucose vested with different leaving and protecting groups and the application of stoichiometric amounts of different promoters was examined with regards to the preparation of the twofold protected PNG. Best results were obtained with 2,3,4,6-tetra-O-acetyl-d-glucopyranosyl fluoride and boron trifluoride etherate (2.0 eq.) as promoter at 0 °C (59%). The deprotection was accomplished stepwise with potassium/sodium hydroxide in acetonitrile/water followed by acid hydrolysis with formic acid resulting in the chemical synthesis of 5'-β-PNG. Microporous and mesoporous minerals are key elements of advanced technological cycles nowadays. Nature-driven microporous materials are known for biocompatibility and renewability. Zeolite is known as an eminent microporous hydrated aluminosilicate mineral containing alkali metals. It is commercially available as adsorbent and catalyst. However, the large quantity of water uptake occupies active sites of zeolite making it less efficient. The widely-used chitosan polysaccharide has also been used in miscellaneous applications, particularly in medicine. However, inferior mechanical properties hampered its usage. Chitosan-modified zeolite composites exhibit superior properties compared to parent materials for innumerable requests. The alliance between a microporous and a biocompatible material with the accompaniment of negative and positive charges, micro/nanopores and proper mechanical properties proposes promising platforms for different uses. In this review, chitosan-modified zeolite composites and their applications have been overviewed. PURPOSE Registered nurses (RN) participate in delivery of routine pediatric preventive care. This pilot study characterized variation in RN roles and overlap with other team roles. METHODS We conducted a pilot cross-sectional survey of RNs from an urban/suburban pediatric primary care network. RNs described tasks during preventive visits and other staff completing similar tasks. Health system data characterized office staffing, volume, and patient population. We assessed whether role overlap and time on key tasks was associated with office characteristics or staffing ratios. RESULTS Twenty-three offices reported a mean ratio of RNs to physicians and nurse practitioners of 0.99 (range 0.62-1.33). Of tasks RNs completed during preventive care, health education overlapped most with physician/nurse practitioner roles (17 sites with overlap) and rooming patients overlapped most with medical assistant roles (20 sites with overlap). Across sites, RNs spent 9% of time on health education and 26% on rooming. Offices with more role overlap between RNs and physicians/nurse practitioners had higher RN to physician/nurse practitioner ratios (1.13 versus 0.86, t-test p-value 0.002). There was no association between role overlap and other office characteristics, or between RN time on key tasks and staffing ratios. CONCLUSIONS RN staffing ratios varied twofold across offices. RNs spent more time on tasks that overlapped with medical assistant roles than tasks that overlapped with physician/nurse practitioner roles. PRACTICE IMPLICATIONS Opportunities exist to optimize RN pediatric primary care roles, for example by delegating certain tasks. Optimization may reduce costs, while improving quality, patient experience, and staff satisfaction.