The preponderance of literature on the repair of proximal hamstring tendon tears focuses on the acute phase (<4 weeks). As such, there is a paucity of data reporting on the outcomes of chronic proximal hamstring tears. To report minimum 2-year postoperative patient-reported outcome (PRO) scores, visual analog scale (VAS) for pain, and patient satisfaction from patients who underwent open or endoscopic repair of partial- and full-thickness chronic proximal hamstring tendon tears. Case series study; Level of evidence, 4. Between April 2002 and May 2017, prospectively collected data from 3 tertiary care institutions were retrospectively reviewed for patients who underwent open and endoscopic repair of partial- and full-thickness chronic proximal hamstring tendon tears. Patients were included only if they had a chronic proximal hamstring tear (defined as ≥4 weeks from symptom onset to surgery). Patients were excluded if they had a tear treated <4 weeks after injury, underwent hamstring reconstructio 1.16 ± 1.92. Patient satisfaction was 8.22 ± 1.20. Patients who underwent open and endoscopic repairs for chronic partial- and full-thickness proximal hamstring tendon tears reported high PROs and satisfaction at a minimum 2-year follow-up with low rates of complications.Patients who underwent open and endoscopic repairs for chronic partial- and full-thickness proximal hamstring tendon tears reported high PROs and satisfaction at a minimum 2-year follow-up with low rates of complications.Thermodynamic uncertainty relations yield a lower bound on entropy production in terms of the mean and fluctuations of a current. Glafenine We derive their general form for systems under arbitrary time-dependent driving from arbitrary initial states and extend these relations beyond currents to state variables. The quality of the bound is discussed for various types of observables for an interacting pair of colloidal particles in a moving laser trap and for the dynamical unfolding of a small protein. Since the input for evaluating these bounds does not require specific knowledge of the system or its coupling to the time-dependent control, they should become widely applicable tools for thermodynamic inference in time-dependently driven systems.The theoretical investigation of nonadiabatic processes is hampered by the complexity of the coupled electron-nuclear dynamics beyond the Born-Oppenheimer approximation. Classically, the simulation of such reactions is limited by the unfavorable scaling of the computational resources as a function of the system size. While quantum computing exhibits proven quantum advantage for the simulation of real-time dynamics, the study of quantum algorithms for the description of nonadiabatic phenomena is still unexplored. In this Letter, we propose a quantum algorithm for the simulation of fast nonadiabatic chemical processes together with an initialization scheme for quantum hardware calculations. In particular, we introduce a first-quantization method for the time evolution of a wave packet on two coupled harmonic potential energy surfaces (Marcus model). In our approach, the computational resources scale polynomially in the system dimensions, opening up new avenues for the study of photophysical processes that are classically intractable.The LIGO-Virgo Collaboration has recently announced the detection of a heavy binary black hole merger, with component masses that are difficult to account for in standard stellar structure theory. In this Letter, we propose several explanations based on models of new physics, including new light particle losses, modified gravity, large extra dimensions, and a small magnetic moment of the neutrino. Each of these affect the physics of the pair instability differently, leading to novel mechanisms for forming black holes inside the mass gap.Charge density waves (CDWs) are understood in great detail in one dimension, but they remain largely enigmatic in two-dimensional systems. In particular, numerous aspects of the associated energy gap and the formation mechanism are not fully understood. Two long-standing riddles are the amplitude and position of the CDW gap with respect to the Fermi level (E_F) and the frequent absence of CDW contrast inversion (CI) between opposite bias scanning tunneling microscopy (STM) images. Here, we find compelling evidence that these two issues are intimately related. Combining density functional theory and STM to analyze the CDW pattern and modulation amplitude in 1T-TiSe_2, we find that CI takes place at an unexpected negative sample bias because the CDW gap opens away from E_F, deep inside the valence band. This bias becomes increasingly negative as the CDW gap shifts to higher binding energy with electron doping. This study shows the importance of CI in STM images to identify periodic modulations with a CDW and to gain valuable insight into the CDW gap, whose measurement is notoriously controversial.Flow coefficients v_n of the orders n=1-6 are measured with the High-Acceptance DiElectron Spectrometer (HADES) at GSI for protons, deuterons, and tritons as a function of centrality, transverse momentum, and rapidity in Au+Au collisions at sqrt[s_NN]=2.4  GeV. Combining the information from the flow coefficients of all orders allows us to construct for the first time, at collision energies of a few GeV, a multidifferential picture of the angular emission pattern of these particles. It reflects the complicated interplay between the effect of the central fireball pressure on the emission of particles and their subsequent interaction with spectator matter. The high precision information on higher order flow coefficients is a major step forward in constraining the equation of state of dense baryonic matter.This Letter investigates what forms of cellular dynamic self-organization are caused through intercellular contact communication based on a theoretical model in which migrating cells perform contact following and contact inhibition and attraction of locomotion. Tuning those strengths causes varieties of dynamic patterns. This further includes a novel form of collective migration, snakelike dynamic assembly. Scrutinizing this pattern reveals that cells in this state can accurately respond to an external directional cue but have no spontaneous global polar order.