Heart auscultation is a convenient tool for early diagnosis of heart diseases and is being developed to be an intelligent tool used in online medicine. Currently, there are few studies on intelligent diagnosis of pediatric murmurs due to congenital heart disease (CHD). The purpose of the study was to develop a method of intelligent diagnosis of pediatric CHD murmurs. Phonocardiogram (PCG) signals of 86 children were recorded with 24 children having normal heart sounds and 62 children having CHD murmurs. A segmentation method based on the discrete wavelet transform combined with Hadamard product was implemented to locate the first and the second heart sounds from the PCG signal. Ten features specific to CHD murmurs were extracted as the input of classifier after segmentation. Eighty-six artificial neural network classifiers were composed into a classification system to identify CHD murmurs. The accuracy, sensitivity, and specificity of diagnosis for heart murmurs were 93%, 93.5%, and 91.7%, respectively. In conclusion, a method of intelligent diagnosis of pediatric CHD murmurs is developed successfully and can be used for online screening of CHD in children.Determining the shade of dental materials is a challenging requirement for the restorative dentist. Improper shade selection is the second cause for laboratory remakes, resulting in inefficiency and additional cost, and unnecessary stress for the clinician and patient. The process of shade selection is somewhat subjective, with no consensus on the protocol. This research investigation aimed to develop a novel software application to provide an accurate, objective, and systematic approach to shade determination for teeth, soft tissues, and dental materials. An IOS software application was developed, termed Smile Shade, to facilitate a simple approach for dental shade determination. Smile Shade functions on a high-dynamic-range microcolor sensor with automatic temperature control and inter-device repeatability of less then 1.0 ∆E. The determination of shade is completed through the evaluation of color based on CMYK, RGB, and LAB, which are different techniques of storing colors. Further research is underway to compare this novel application to the traditional shade tab approach commonly practiced at most dental schools.This paper reports a novel, minimally invasive, simple technique for the treatment of a displaced dentoalveolar fracture using a vacuum-formed splint in a 12-year-old pediatric patient. Vacuum formed splints have been reliable treatment options with limited morbidity and discomfort compared to other traditionally used procedures.Background. The effectiveness of fissure sealants in caries prevention depends on their long-term retention and ability to stop caries progression. This randomized controlled clinical trial compared the retention rate and cariostatic properties of a contemporary glass-ionomer-based sealant (GIS) versus a resin-based sealant (RS) placed on fully erupted permanent molars in a split-mouth design. Methods. The sealants were placed on fully erupted permanent teeth (8‒12 years of age) in 45 children. The evaluation was conducted after one week and three and six months. Results. There was a statistically significant difference in the retention rate and caries transition between the two groups over a six-month clinical evaluation period. The resin-based sealant group showed a better retention rate than the GIS group (75.56% and 48.88%, respectively). IWP-4 nmr The resin-based sealant was superior to GIS in preventing caries progression. Conclusion. Resin-based fissure sealant with fluoride releasing properties might be preferable in preventing caries progression of incipient non-cavitated carious lesions in fully-erupted teeth.Background. In sliding mechanics, archwires should slide easily during the retraction of anteriors. Round wires slide well, but the torque control is a significant problem. Rectangular wires produce effective torque expression but pose a challenge to free sliding due to factors like friction and force used to overcome friction, etc. To utilize the properties of both wires, the wire should be bi-dimensional. Dual-dimensional wire is one such wire with different dimensions in the anterior and posterior sections. This study aimed to compare the amount of space closure and anchorage loss of molars between the rectangular and dual-dimensional wire groups during retraction with mini-implants. Methods. Forty patients were randomly allocated to two groups (n=20). Patients with rectangular wires formed the control group, and those with dual-dimensional wires formed the experimental group. Mini-implants and NiTi coil springs were used for retraction. Model and cephalometric analyses were carried out to calculate the amount of space closure and anchor loss, before and four months after the study. Statistical significance was set at P less then 0.05. Results. The average amount of space closure was higher with DDW (3.98 mm) than rectangular wire (3.22 mm). The difference was statistically significant. No significant difference was found with anchorage loss. Conclusion. DDW can be used as an alternative to rectangular wires during retraction with mini-implants; however, it cannot replace the rectangular wires completely. Anchorage control was effective with both wires.Background. Immediate single implant placement and restoration (IIR) is recognized as a novel method and is the main request of many patients. This study was designed to evaluate the aesthetic outcomes of immediately restored single implants placed in extraction sockets in theanterior maxilla. Methods. In this case series study, 18 patients were selected from two private clinics after placing a single-tooth implant in the anterior maxilla. Immediate provisional crowns were delivered on the following day or at most 48 hours later, and guidelines were provided. The Pink Esthetic Score (PES) questionnaire was used at 6- and 12-month follow-ups to assess aesthetic outcomes. Data were analyzed with single t-test and dependent t-test. Results. In general, the results showed that the status of the mesial papilla, distal papilla, curve of the facial soft tissue line, level of the facial peri-implant mucosa and root convexity soft tissue in IIR method were optimal (P less then 0.05), with total PES means of 9.44±0.783 and 8.