77. As conclusions, the scale exhibited a unidimensional structure similar to that in other studies and presented good reliability values. Hence, its use is recommended to screen suicidal ideation in school-aged adolescents in Santa Marta, Colombia. Emerging studies have identified that long non-coding RNAs (lncRNAs) play critical roles in cancer development. This study aims to explore the mechanism of NF-KappaB (NF-κB) interacting lncRNA (NKILA) in the pathological process of oral squamous cell carcinoma (OSCC). NKILA expression in OSCC tissues, paracancerous tissues, and normal human oral keratinocytes and OSCC cell lines was detected using RT-qPCR. KB cells were selected for the follow-up experiments. The role of NKILA in cell proliferation, migration, invasion, and NF-κB signaling pathway was identified using the gain- and loss-of function of NKILA in OSCC cells. Additionally, the role of NKILA was determined by inducing xenograft tumors in nude mice. NKILA was poorly expressed in OSCC tissues and cells. Cell proliferation, invasion and migration, tumor volume and weight were significantly suppressed in cells with overexpressed NKILA, while silencing NKILA led to opposite trends. Moreover, the protein levels of p-IκBα and nuclear-p65 were markedly decreased, while the levels of IκBα and cytoplasm-p65 were enhanced in cells with overexpressed NKILA. This study provided evidence that NKILA could reduce proliferation, invasion and migration of OSCC cells through inhibiting the NF-κB signaling pathway. The findings may offer new insights for OSCC prevention and treatment.This study provided evidence that NKILA could reduce proliferation, invasion and migration of OSCC cells through inhibiting the NF-κB signaling pathway. The findings may offer new insights for OSCC prevention and treatment.Electrospun nanofibers is a promising and versatile avenue for building controlled drug release system because of the facile fabrication and the broad range of polymer materials. This research systematically studied the morphological effect of thermosensitive electrospun nanofibers, including porous and coaxial structures, on controllable drug release. Three types of drugs, nicotinamide, paracetamol, and ibuprofen, with different hydrophilicity were applied in this study. The data of drug release were all fitted to the first-order kinetic model regardless of the drug properties, and the release rates paralleled with their hydrophilicity. Sol-gel phase transition of the thermosensitive poly(N-isopropylacrylamide) (PNIPAAm) hydrogel led to slower drug release at 37°C compared with those at 25°C. Regarding morphology, coaxial nanofibers could provide higher loading efficiency and slower drug release rather than porous nanofibers. Our research highlighted the overall effects of compound property, temperature, and the morphological structures of thermosensitive electrospun nanofibers on the controlled drug release. Our results concluded that hydrophobic drug encapsulated in the core-shell PNIPAAm nanofibers could perform excellent sustained release and also controllable release under temperature stumuli.This study elucidated spatiotemporal and ground reaction force determinants of running speed and acceleration for female sprinters during the entire sprinting. Fifteen female sprinters completed 60 m sprints. Kinematic and kinetic variables were measured using force platforms over a 50 m distance from the start. Results demonstrated that higher step frequency (11th-27th steps, r = 0.517-0.717) through shorter support time (12th-27th steps, r = -0.535 to -0.634) could be determinants of running speed. Moreover, increasing step length (1st-10th steps, r = 0.550-0.938), suppressing increases in step frequency (2nd-7th steps, r = -0.639 to -0.870), suppressing decreases in support time (1st-5th steps, r = 0.599-0.709) and increases in flight time (4th-7th steps, r = 0.523-0.649) can be essential for greater running acceleration. Propulsive mean force (1st-5th steps, r = 0.663-0.876) and anteroposterior net mean force (all steps, r = 0.697-0.894) are likely determinants of greater running acceleration. At the maximal speed phase there was no correlation between running speed and the other variables. Differences with previously found male sprint determinants suggest that training targets specific to female sprinters are necessary for improving training designs and race strategy.To evaluate and compare the performances of different adsorbents for gas separation, an adsorbent comprehensive evaluation indicator (ACEI) is proposed. In the ACEI, the working capacity, selectivity, adsorption rate, regeneration and circulation parameters, stability during adsorption, and tolerance to impurities are considered, and some exponents are introduced to allow the ACEI to adapt to different adsorbent working conditions. To illustrate the applicability of the ACEI, the adsorption of CO2 and N2 was investigated on two kinds of activated carbons (ACs), which were used for gas purification and bulk separation. The ACEI is a better overall indicator than other currently used indicators to evaluate the performance of adsorbents.Theoretical work in resilience has continuously evolved to inform and respond to advances in empirical work. In order to further scientific inquiry, it must continue to do so. This narrative overview of the field of resilience science focuses on contemporary challenges confronted by theoretical models of individual resilience and proposes a taxonomic structure for resilience-the multidimensional taxonomy of individual resilience (MTIR). The goal of the MTIR is to articulate a systematic framework within which extant theoretical and empirical work can be nested. Consistent with existing work, the MTIR organizes resilience into two primary branches-manifested resilience and generative resilience. These two components are then organized into subdomains that demonstrate evidence of conceptual distinctiveness. learn more The specification of the subdomains in the MTIR draws support from a diverse body of work on resilience across disciplines and in multiple global contexts. The MTIR makes several critical advances, including expanding and refining the definitions and components of resilience in psychology, providing a clearer framework for conceptualizing mixed profiles of resilience, and tempering assumptions regarding the relational dependencies across domains of resilience.