AIMS Experiencing an acute myocardial infarction (AMI) is a life-threatening event and use of statins can reduce the probability of recurrence and improve long term survival. However, the effectiveness of statins in the real-world setting may be lower than the reported efficacy in randomized clinical trials. Therefore, we aimed to investigate whether low statin treatment adherence during the year following an AMI episode associated with increased second year mortality. METHODS AND RESULTS We analysed all 54,872 AMI patients aged ≥45 years, admitted to Swedish hospitals between 2010-2012, and who survive at least one year after the AMI episode. We defined low adherence as a medication possession ratio less then 50% or non-use of statins. Applying inverse probability of treatment weighting (IPTW) we investigated the association between low adherence and all-cause, cardiovascular (CVD), and non-CVD mortality during the second year.Overall 20% of the patients had low adherence during the first year, and 8% died during the second. In the IPTW analysis, low adherence was associated with an increased risk of all-cause (Absolute risk difference (ARD) =0.048, Number Need to Harm (NNH) =21, Relative Risk (RR) =1.71), CVD (ARD=0.035, NNH=29, RR = 1.62) and non-CVD mortality (ARD=0.013, NNH=77, RR = 2.17). CONCLUSION In the real-world setting, low statin adherence during the first year after an AMI episode is associated with increased mortality during the second year. Our results reaffirm the importance of achieving a high adherence to statin treatment after suffering from an AMI. © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology.We sequenced the entire tb1 gene in six maize inbreds and its wild relatives (parviglumis, mexicana, perennis and luxurians) to characterize it at molecular level. Hopscotch and Tourist transposable elements were observed in the upstream of tb1 in all maize inbreds, while they were absent in wild relatives. In maize, tb1 consisted of 431-443 bp 5'UTR, 1101 bp coding sequence and 211-219 bp 3'UTR. In promoter region, mutations in the light response element in mexicana (~ 35 bp and ~ 55 bp upstream of TSS) and perennis (at ~ 35 bp upstream of TSS) were found. A 6 bp insertion at 420 bp downstream of the polyA signal site was present among teosinte accessions, while it was not observed in maize. A codominant marker flanking the 6 bp InDel was developed, and it differentiated the teosintes from maize. In Tb1 protein, alanine (12.7-14.6%) was the most abundant amino acid with tryptophan as the rarest (0.5-0.9%). The molecular weight of Tb1 protein was 38757.15 g/mol except 'Palomero Toluqueno' and HKI1128. R and TCP motifs in Tb1 protein were highly conserved across maize, teosinte and orthologues, while TCP domain differed for tb1 paralogue. Tb1 possessed important role in light-, auxin-, stress-response and meristem identity maintenance. Presence of molecular signal suggested its localization in mitochondria, nucleus and nucleolus. Parviglumis and mexicana shared closer relationship with maize than perennis and luxurians. A highly conserved 59-60 amino acids long bHLH region was observed across genotypes. Information generated here assumes significance in evolution of tb1 gene and breeding for enhancement of prolificacy in maize. © King Abdulaziz City for Science and Technology 2020.High-contrast angular intensity fringes are generated by reflecting laser light from an uncoated spiral phase plate (SPP) device for the first time, to the best of our knowledge. As the laser frequency going into the device is tuned, the fringes rotate. Measured transverse fringe patterns match their theoretical predicted values. They have unity contrast, and their measured intensity varies with laser frequency in a fashion similar to a Fabry-Perot etalon. This effect can be used to enable new miniature devices for angle metrology, imaging, and microscopy.We demonstrate secure optical coherent communications employing low-coherence matched detection based on the randomness of amplified spontaneous emission (ASE) noise. Two-level physical-layer optical encryption is achieved through temporal and spectral coding over a broadband ASE source. An ASE-carried signal and unmodulated carrier are polarization multiplexed, transmitted over a same single-mode fiber (SMF), and separated with the aid of polarization tracking before having matched detection at the receiving side. The impact of chromatic dispersion on the low-coherence matched detection system is analyzed and experimentally investigated. We experimentally realize optically coded 20 Gbaud QPSK and 8-PSK signals transmission over a 43 km SMF span with a maximum line rate of 60 Gbits/s.Intensive research in photonics has discovered many original and fascinating optical phenomena associated with the physics of Fano resonances. https://www.selleckchem.com/products/sovilnesib.html Here we extend the research of Fano resonance to on-chip multiple modes and high-order mode, which can be called multimode Fano resonance. By exploiting both wavelength and mode degrees of freedom, we demonstrate a compact structure to engineer wavelength- and shape-controlled multimode Fano resonances on an integrated photonic platform. Both simulated and experimental results indicate that the unambiguous asymmetric spectra line shapes for both transverse electric modes ($\rm TE_0$TE0 and $\rm TE_1$TE1) can be further applied to low-power mode switching. The demonstrated on-chip multimode Fano resonances scheme may provide a new perspective for exploring the advantages and applications of multimode Fano resonances in integrated photonics.Existing random phase screen (RPS) models for forward multiple-scattering media fail to incorporate ballistic light. In this Letter, we redesign the angular spectrum of the screen by means of Monte Carlo simulation based on an assumption that a single screen should represent all the scattering events a photon experiences between two adjacent screens. Three examples demonstrate that the proposed model exhibits more realistic optical properties than conventional RPS models in terms of attenuation of ballistic light, evolution of beam profile, and angular memory effect. The proposed model also provides the flexibility to balance the computing accuracy, speed, and memory usage by tuning the screen spacing.