Although the health of the snails exposed to Cd, Hg and PAHs was altered, TL length in haemocytes was not disturbed, suggesting a high capacity of this snail species to maintain its TLs in haemocytes under chemical stress. These results first address TL length in snails and reveal that the relationship commonly proposed for vertebrates between TL shortening and ageing or exposure to contaminants cannot be generalized.Despite of significant progress in remediation of Cr(VI) or Hg(II) pollution by microorganisms, study on the reduction of both Cr(VI) and Hg(II) by the same microbial strain was not reported so far, which is actually important for bioremediation of contaminated sites with multiple heavy metals. In this study, Pseudomonas umsongensis CY-1 was newly isolated from chromium-contaminated soil and showed remediation potentials for both Cr(VI) and Hg(II) pollution. The highest Cr(VI) (93.9%) and Hg(II) (82.8%) reduction rates were obtained at the initial concentration of 5 mg/L. Comparison between removal by resting cells and heat-treated resting cells demonstrated that P. umsongensis CY-1 removed Cr(VI) and Hg(II) from Tris-HCl buffer (pH 7.0) mainly through reduction instead of adsorption. By comparing the Cr(VI) and Hg(II) reduction rates of different cellular fractions, it was found that Cr(VI) and Hg(II) reductions mainly happened in the cytoplasm of P. umsongensis CY-1, which were further demonstrated by Transmission electron microscopy (TEM) analysis. Furthermore, analysis of X-ray photoelectron spectroscopy demonstrated that the reduction products of Cr(VI) and Hg(II) were mainly in the form of Cr(III) and Hg (0), respectively. The findings in this study will provide a guide for further insights in the bioremediation of contaminated sites with multiple heavy metals.Background Incorporating consumers' voices in tertiary education curricula is an ongoing initiative of educators of health professions in order to facilitate students' readiness for consumer-based practice and to meet accreditation standards. Consequently, educators within these professions use a range of different strategies to involve, recruit and retain consumers. To date, no study has attempted to consolidate the different strategies used by nursing, midwifery and allied health educators to involve, recruit and retain consumers. buy FGF401 Consolidating these strategies will lead to a sharing of ideas, which would be of benefit to educators looking for ways to involve consumers in their programs. Objectives This scoping review aimed to identify how consumers are involved, recruited and retained in nursing, midwifery and allied health curricula, as reported within research from these professions. Design The scoping review was carried out and reported according to the PRISMA Extension for Scoping Reviews. Data sourcesapped across the studies. Conclusion The collated findings allow idea sharing among educators from these professions on the various types of consumer involvement, recruitment and retention strategies. Enriching tertiary education programs with consumer input enhances student learning and assists these professions to meet accreditation standards.Background Direct observation is a common assessment strategy in health education and training, in which trainees are observed and assessed while undertaking authentic patient care and clinical activities. A variety of direct observation tools have been developed for assessing competency in delivering person-centred care (PCC), yet to our knowledge no review of such tools exists. Objective To review and evaluate direct observation tools developed to assess health professionals' competency in delivering PCC. Design State-of-the-art review DATA SOURCES Electronic literature searches were conducted in PubMed, ERIC, CINAHL, and Web of Science for English-language articles describing the development and testing of direct observation tools for assessing PCC published until March 2017. Review methods Three authors independently assessed the records for eligibility. Duplicates were removed and articles were excluded that were irrelevant based on title and/or abstract. All remaining articles were read in full text. A ugh all may serve formative purposes, evidence supporting their use in summative evaluations is limited. Patients were not involved in the development of any tool, which seems intrinsically paradoxical given the aims of PCC. The tools may be useful for providing trainee feedback; however, rigorously tested and patient-derived tools are needed for high-stakes use.Background The number of people with neurocognitive disorder is increasing, and the majority of them are cared for by informal caregivers in the community. Mental health problems are common among caregivers, however, professional support for them is often limited. Non-pharmacological self-help interventions, such as bibliotherapy, may improve mental well-being and has the potential for being integrated into clinical or social services. Objectives To explore what types of bibliotherapy have been used for improving the mental well-being of informal caregivers of people with neurocognitive disorders, and the effect on mental well-being outcomes. Design A systematic review and meta-analysis. Review methods Six databases were searched for relevant articles on July 1, 2019. Clinical trial registries and the reference lists of included studies were also searched. Both randomized controlled trials and quasi-experimental studies were included. The Cochrane Collaboration risk of bias tool for randomized controlled tria with problem behaviours at Z = 2.44 (I2 = 0, SMD = 0.36, 95%CI = 0.05 to 0.67, p = .02), however, the effect on self-efficacy for obtaining respite was not significant (I2 = 0, SMD = 0.17, 95%CI = -0.16 to 0.49, p = .32). The effect on decreasing state anxiety was significant at Z = 2.30 (I2 = 22%, SMD = -0.22, 95% CI = -0.41 to -0.33, p = .02). Conclusions Bibliotherapy showed positive effects on reducing depression, improving self-efficacy for dealing with problem behaviors and reducing anxiety among informal caregivers. The effects on reducing depression should be viewed with caution due to high heterogeneity. The effects on other mental well-being outcomes are inconclusive due to limited number of studies and this underscores the need for further research.