Bisphenol analogues (BPs) have been widely used in industrial production as substitutes of bisphenol A (BPA). The demand and production of BPs are growing rapidly in China. In this study, the pollution levels and distribution characteristics of five BPs were investigated in surface water from rivers located in different land-use types of an ecological demonstration zone. All BPs were detected at least once in the traditionally dissolved phase, colloidal phase and suspended particulate matter (SPM) with the mean total concentrations of 465.1 ng L-1, 114.4 ng L-1 and 11.3 μg g-1 dry weight, respectively. Potrasertib BPA is the dominant BP in the traditionally dissolved phase and colloidal phase, with the mean contribution rates of 77.6% and 70.7%, respectively, followed by bisphenol F (BPF) and/or bisphenol S (BPS). The colloids as the important sinks of contaminants contributed 42.3% of bisphenol Z, 37.3% of BPF, 24.9% of BPA, 22.3% of BPAF and 18.4% of BPS in the traditionally dissolved phase. However, BPA alternatives are found primarily in the SPM, in which the contribution rate of BPA ranges from 0.6% to 48.1%, with the mean contribution of 12.4%. Based on BP concentrations in the traditionally dissolved phase, moderate ecological risk levels of BPA and BPF towards aquatic organisms were posed. Fish and/or algae are the most sensitive aquatic organisms, and hence chronic toxicological effects should not be ignored especially in fish.Daidzein (DAI) is a kind of natural isoflavonic phytoestrogen with estrogenic activity. However, little is known about its influence on early fetal growth in mammalian animals. The current study aimed to explore the characteristics of amniotic fluid exposure to dietary DAI using 1H NMR-based metabolomics and biochemical analysis. Here, we found that DAI supplementation at a dose of 200 mg kg-1 significantly enhanced the number of viable embryos at the early gestation stage (P less then 0.05). DAI significantly elevated the concentrations of estrogen (E) and insulin-like growth factor-I (IGF-I) in the amniotic fluid (P less then 0.05). Moreover, DAI tended to increase the concentration of progesterone, but decrease the concentration of tumor necrosis factor α (TNF-α) in the amniotic fluid (0.05 less then P less then 0.10). Interestingly, the activity of glutathione peroxidase (GSH-Px) was higher in the DAI group than in the CON group (P less then 0.05). An 1H NMR-based metabolomics analysis identified and quantified more than 30 compounds in the amniotic fluid, and some critical metabolites such as arginine, creatine, and citrate were found to be significantly elevated upon DAI supplementation (P less then 0.05). Importantly, the metabolic pathways involved in arginine and proline metabolisms were found to be significantly affected by DAI. Collectively, dietary DAI may improve embryo survival by improving hormones, antioxidant capacity, and metabolic profiles in the maternal amniotic fluid.We report a cost-effective, straightforward synthesis of a novel electrocatalyst for the reduction of CO2 to formate, which achieves nearly complete Faradaic efficiency (FE) at an overpotential (η) of 0.88 V under ambient conditions. The electrocatalyst was prepared using bismuth subsalicylate as precursor and consists of bismuth nanoparticles (Bi NPs) with an average diameter of 5.5 nm supported on activated carbon.Two-dimensional Mo2C materials (1T and 2H phases) have emerged as promising electrocatalysts for the hydrogen evolution reaction (HER) due to their low cost, inherent metallicity, and high stability. Unfortunately, the catalytic activity of Mo2C is lower than that of Pt, and it needs to be substantially improved for practical applications. It is necessary and urgent to consider the effect of synergetic interactions among defects, functions, and strain on the HER activity. In this study, the geometric structures, electronic properties, and the HER activity of the Mo2C monolayer, with vacancy defects (i.e. Mo and C), oxygen functionalization, and strain, are studied by using first-principles calculations. According to our results, the combination of Mo vacancies, which can be obtained under C-rich conditions, and oxygen functionalization is the most effective way to improve the HER activity of 1T- and 2H-Mo2C. Considering the abundant active sites and optimal Gibbs free energy of hydrogen adsorption, the 1T phase we obtained shows excellent HER activity even at high H coverage and improves the utilization of active sites, for which the HER activity is comparable to that of Pt. This can be attributed to the fact that oxygen atoms gain more electrons from Mo2C, which weakens the strength of the O-H bond. Our work provides not only an opportunity to better understand the catalytic mechanism, but also a guide to achieving high HER activity of a Mo2C monolayer.Strigolactones (SLs) are plant hormones that suppress shoot branching through perception by their receptor protein DWARF 14 (D14). The artificial regulation of SL signaling has been considered a potent agricultural technique because plant architecture is strongly related to crop yield. In this communication, we describe the development of a small-molecule D14 inhibitor that functions at sub-micromolar levels. This potent inhibitor may be a lead compound for a first-in-class plant growth regulator.Buckybowls have concave and convex surfaces with distinct π-electron cloud distribution, and consequently they show unique structural and electronic features as compared to planar aromatic polycycles. Doping the π-framework of buckybowls with heteroatoms is an efficient scheme to tailor inherent properties, because the nature of heteroatoms plays a pivotal role in the structural and electronic characteristics of the resulting hetera-buckybowls. The design, synthesis, and derivatization of hetera-buckybowls open an avenue for obtaining fascinating organic entities not only of fundamental importance but also of promising applications in optoelectronics. In this review, we summarize the advances in hetera-buckybowl chemistry, particularly the synthetic strategies toward these scaffolds.