The development of organic room-temperature phosphorescence (RTP) is accompanied by opportunities and challenges. RTP from crystal polymorphism has aroused much attention, due to the significant different photophysical characteristics and intermolecular packings found in the same molecule with different crystal phases. Herein, we report three organic molecules BP-o-BO, BP-m-BO, and BP-p-BO, in which two crystal polymorphisms of BP-p-BO are successfully cultivated with different emission properties. learn more BP-p-BO-A exhibits bright cyan photoluminescence (PL) with a quantum yield of 11.3% and a distinct RTP with a lifetime of 17.1 ms, which is much higher than the deep blue PL of BP-p-BO-B (6.9%) and the corresponding RTP lifetime of 3.3 ms. Crystal structure analyses indicate that the different emission properties can be ascribed to the different intermolecular packing, further demonstrating the essential role of molecular packing in the designing of RTP materials.Benchtop NMR spectrometers have become widely available over the last decade. They are now used successfully in various branches of chemistry. Their popularity continues to grow due to their low price and almost zero running costs. However, benchtop spectrometers suffer from low resolution and sensitivity compared to the high-field spectrometers used in NMR labs for several decades. In this article we present a solution for boosting the sensitivity of benchtop NMR spectrometers in a multi-scan experiment and improving their capabilities in quantitative measurement. Our solution involves the synchronized shifting of a sample to preserve its high nuclear polarization during the measurement. We performed several experiments using different samples to confirm this improved performance an 1H NMR experiment for 4,4-dimethoxy-2-butanone, and 13C NMR experiments for benzyl salicylate, the liquid pharmaceutical product Acerin (skin solution), and a mixture of m-anisaldehyde and (R)-(+)-limonene.Trisresorcinarene is an interesting class of macrocyclic host. Its insoluble nature and conformationally flexible structure allow its application as a solid absorbent. Various aromatic and aliphatic hydrocarbons are absorbed into the amorphous solid of the trisresorcinarene, demonstrating the versatile absorption capability of trisresorcinarene. The Spanish registry of Covid-19 in Spanish pregnant women, made up of 100 centers, is created in response to the need to know the morbidity that Covid-19 generates in pregnant women and their newborns, to know the real incidence of the disease in this population group and to establish and monitor the package of measures to improve their care. The aim of this paper was the creation of a registry of pregnant women with Covid-19 infection in order to establish the interventions and measures necessary to improve the care of these patients during hospital admission. To prepare the registry, the main researcher of each center collected weekly / biweekly the number of total pregnant women screened, as well as the total number of positive and negative, sending these data to the responsible researchers so that it could be available in real time of the percentage of infected asymptomatic pregnant population and the evolution by weeks in the centers of each participating province. The data were analyzed using the lserving a significant decrease in the proportion of positive pregnant women over the total of screenings throughout this period, with an average of 6.5% in early April 2020 to an average of 0.93% positive in late May 2020.BACKGROUND Immunotherapy is one of the research hotspots in the field of hepatocellular carcinoma (HCC). Successive clinical trials have shown that patients with CTNNB1 mutations are resistant to immunotherapy, but the mechanism is still unclear. MATERIAL AND METHODS We identified differentially expressed immune genes (DEIGs) in patients with and without CTNNB1 mutations in the Cancer Genome Atlas (TCGA) database and then paired them to explore any correlation with prognosis. Univariate Cox regression analysis and Lasso regression analysis were used to develop the prognostic model. We first divided the TCGA cohort into 29 subgroups for internal validation and then used the International Cancer Genome Consortium (ICGC) cohort to conduct external validation. We also used a CIBERSORT algorithm to quantify immune infiltration of the different risk groups. RESULTS The novel prognostic model consisted of 45 immune-gene pairs with general applicability. It was more accurate than the traditional prognostic signature, which is based on gene expression by comparison of area under the receiver operating characteristic curve (AUC) values. The infiltration proportion of B cells, CD8 T lymphocytes, activated natural killer cells, and M1 macrophages in the low-risk group was greater in the high-risk group, while the infiltration proportion of M0 and M2 macrophages was greater in the high-risk group. CONCLUSIONS In this study, a novel approach was proposed for evaluating HCC prognosis, which may be useful in evaluatingthe intensity of the immune response in the HCC microenvironment.Intralabyrinthine schwannoma (ILS) is a rare benign tumor affecting cochlear and vestibular nerves, whose symptoms are generally unspecific and frequently responsible for a late diagnosis. Radiological examinations, with particular reference to magnetic resonance imaging (MRI), represent the only diagnostic technique to identify ILS. On computed tomography ILS can only be indirectly suspected by the presence of surrounding bone remodeling, whereas MRI provides direct visualization of the neoplasm as a filling defect within the labyrinth with vivid contrast enhancement. At the same time, MRI is also helpful in defining ILS anatomical extension into adjacent structures and in planning therapeutic management. Here we report three representative cases of ILS with new pictorial imaging features to improve ILS early detection and optimize subsequent therapeutic management.Spondylodiscitis (SD) is one of the main causes of back pain. Although the low mortality, high morbidity is related to spondilodiscitys, leading spine instability, chronic pain or neurological deficit. Diagnostic imaging plays a primary role in diagnosing spondylodiscitis. However different accuracy is highlighted by different diagnostic tool, depending also on timing of disease which represents a cardinal element for the phenotypic manifestation of the disease, beyond spatial resolution and tissue characterization proper of specific modality imaging. Conventional Radiology (CR), Computed Tomography (CT) and MRI (Magnetic Resonance Imaging) all have proven to be of primary importance in the approach to spondylodiscitis, although magnetic resonance imaging has demonstrated the greatest advantage in identifying the disease from its earliest stages, demonstrating high sensitivity and specificity (92% and 96%, respectively). This review focus on the role of different imaging modality in the approach to the spondylodiscitis, also addressing the role of interventional radiology that is pivotal not only for a diagnosis of certainty through biopsy, but also for a minimally-invasive treatment of paravertebral abscesses spondylodiscitis-related.