2% and 0.4%, respectively. It is reasonable to offer CMA as a first-tier test to fetuses with MVM. However, for fetuses with other USMs, the considerations to perform CMA should not differ from pregnancies with normal ultrasound.It is reasonable to offer CMA as a first-tier test to fetuses with MVM. However, for fetuses with other USMs, the considerations to perform CMA should not differ from pregnancies with normal ultrasound.The present study was aimed to develop Manihot esculenta and Carrageenan bio-based composite active film functionalized with anise, caraway, and nutmeg essential oils (EOs) and to assess the shelf life of chicken nuggets wrapped with the developed film at refrigeration storage. Overall, the Minimum Inhibitory Concentration (MIC) values of the three EOs ranged from 0.4 to 0.8% v/v of which nutmeg EO was found most effective. Incorporation of EOs in the film resulted in significant (P ˂ 0.05) decrease in tensile strength and water activity while elongation at break was significantly (P ˂ 0.05) increased. Estradiol ic50 No significant (P ˃ 0.05) changes in thickness and Water Vapor Transmission Rate (WVTR) were observed. Based on physicomechanical and sensory evaluation, films incorporated with 0.5, 1, and 1% concentration of anise, nutmeg, and caraway EO were selected. Chicken nuggets overwrapped with aforementioned films were stored aerobically at refrigeration temperature (4 ± 1 °C) to evaluate antimicrobial, antioxidant, aties based on requirements of product-specific packaging conditions.Reconstructing locomotor behaviour for fossil animals is typically done with postcranial elements. However, for species only known from cranial material, locomotor behaviour is difficult to reconstruct. The semicircular canals (SCCs) in the inner ear provide insight into an animal's locomotor agility. A relationship exists between the size of the SCCs relative to body mass and the jerkiness of an animal's locomotion. Additionally, studies have also demonstrated a relationship between SCC orthogonality and angular head velocity. Here, we employ two metrics for reconstructing locomotor agility, radius of curvature dimensions and SCC orthogonality, in a sample of twelve fossil rodents from the families Ischyromyidae, Sciuridae and Aplodontidae. The method utilizing radius of curvature dimensions provided a reconstruction of fossil rodent locomotor behaviour that is more consistent with previous studies assessing fossil rodent locomotor behaviour compared to the method based on SCC orthogonality. Previous work onstcranial reconstruction as fossorial and with previous indications that early aplodontids were more arboreal than their burrowing descendants. The presence of a gendered subdivision of labor has been bioarchaeologically investigated in various prehistoric and historical contexts. Little is known, however, about the type of differences in daily activities characterizing men and women among the Celtic communities of Italy. The focus of the present study is the analysis of differences in patterns of entheseal changes (ECs) and long bone shape and robusticity between sexes among the Cenomani Gauls of Seminario Vescovile (SV-Verona, Italy, third-first century BC). The sample includes 56 adult individuals (22 females and 34 males). Presence of ECs on nine bilateral postcranial attachment sites, and values of humeral and femoral shape and robusticity indices based on external measurements were compared between sexes by means of generalized linear models and Mann-Whitney tests. Results show a lack of difference between sexes in long bone shape and robusticity, and a higher incidence of upper and, especially, lower limb ECs in males. These results suggest the presence of sex-specific activities at SV mostly related to farming and differently influencing the considered variables. Also, this study suggests the relevance of a series of nonbiomechanical factors (developmental, hormonal, genetic, and methodological) when attempting biocultural reconstructions from osteoarchaeological samples.These results suggest the presence of sex-specific activities at SV mostly related to farming and differently influencing the considered variables. Also, this study suggests the relevance of a series of nonbiomechanical factors (developmental, hormonal, genetic, and methodological) when attempting biocultural reconstructions from osteoarchaeological samples. Previous preterm birth is a strong predictor of subsequent preterm birth, but less is known about the causes of preterm birth following a full-term first pregnancy. Recent research has highlighted previous caesarean section as a potential risk factor. To examine the relationship between mode of first birth and the risk of subsequent preterm birth in New South Wales (NSW), Australia. A population-based record-linkage study of NSW women who had a live singleton first birth at ≥37weeks gestation, followed by a singleton second birth between 2005 and 2017. Relative risk (RR) and 95% CI of preterm birth in the subsequent pregnancy was calculated using modified Poisson regression, with mode of first birth as the exposure. Spontaneous preterm birth and preterm prelabour caesarean were secondary outcomes. Women who had either an intrapartum (RR 1.26, 95% CI 1.19-1.32) or prelabour caesarean (RR 1.26, 95% CI 1.18-1.35) first birth had a higher risk of subsequent preterm birth (any birth <37weeks gestation), than those who birthed vaginally. Women who had a previous instrumental birth (RR 0.85, 95% CI 0.79-0.91) or prelabour caesarean (RR 0.74, 95% CI 0.67-0.82) had lower risks of subsequent spontaneous preterm birth. However, prior prelabour caesarean also greatly increased risk of subsequent preterm prelabour caesarean (RR 5.25, 95% CI 4.65-5.93). The mode of first birth has differing effects on the risk of subsequent spontaneous preterm birth and preterm prelabour caesarean. Awareness of the risk of subsequent preterm birth following caesarean section may help inform clinical decisions around mode of first birth.The mode of first birth has differing effects on the risk of subsequent spontaneous preterm birth and preterm prelabour caesarean. Awareness of the risk of subsequent preterm birth following caesarean section may help inform clinical decisions around mode of first birth.